Fig. 6

The state of oxidative stress and apoptosis in the liver (n = 6). A HE staining of liver (Black arrows indicate hemorrhagic spots), magnification 200×. B Ultrastructural analysis of liver (Black arrows indicate mitochondrial swelling, white arrows indicate abnormal nuclear morphology), magnification 15,000×. C Relative mRNA expression of ER stress genes. D Relative mRNA expression of apoptotic genes. E Relative mRNA expression of the Nrf2-mediated antioxidant systems genes. F Protein expression of oxidative stress and apoptosis (n = 3). G Activity of oxidative stress-related enzymes and markers. ^a,bValues without the same letters within the same line indicate a significant difference (P < 0.05)