Fig. 9

Visualization of the biological gene ontology analysis of the proteins involved in the reproductive process annotation in extraembryonic membranes of pregnant sows at d 18 and 24 of gestation. The size of the nodes indicates the pathway´s enrichment significance. The following ClueGO parameters were used: P-value cut-off = 0.001; Statistical test used the enrichment/depletion (two-sided hypergeometric test); Bonferroni step down with minimum GO level 2; maximum GO level 6; kappa score threshold equal to 0.4. GO = Gene Ontology. Network includes the interaction of CCDC134, HSD17B2, HSP90AB1, KRT19, MAPK14, NOTCH2, PRDX3, PTGS2, RTCB, ST14, ACE, APOB, BAX, CCDC134, CDK1, CELF1, CTNNB1, DHX36, DLG1, HSD17B2, ITGB4, KDR, KRT19, LRP2, MSH2, NOTCH1, NOTCH2, PAFAH1B1, PDGFRA, PRKACA, RAD23B, RTCB, SEPTIN7, SMAD1 and ST14 proteins