Fig. 4

Visualization of the biological gene ontology analysis of unique proteins involved in the reproductive process annotation in pregnant sows. The size of the nodes indicates the pathway´s enrichment significance. The following ClueGO parameters were used: P-value cut-off = 0.001; Statistical test used the enrichment/depletion (two-sided hypergeometric test); Bonferroni step down with minimum GO level 2; maximum GO level 6; kappa score threshold equal to 0.4. GO = Gene Ontology. Network include the involvement of HECTD1, HSD17B2, MAP2K1, MAPK14, RPS6, MSH2, DLG1 and INHBB proteins among others