Fig. 3

Visualization of the reactome pathways analysis of unique proteins involved in immune system process (A) and biological adhesion annotation (B) in pregnant sows. The size of the nodes indicates the pathway´s enrichment significance. The following ClueGO parameters were used: P-value cut-off = 0.05; Statistical test used the enrichment/depletion (two-sided hypergeometric test); Bonferroni step down with minimum GO level 2; maximum GO level 6; kappa score threshold equal to 0.4. GO = Gene Ontology. Network (A) includes the interaction of CCR5, HMOX1, IFI35, ISG15, LBP, MAP2K1, MAPK14, SLA, STXBP2, VAMP7, CD14, DNM1, LBP, MAP2K1, MAPK14 and S100A9 proteins