Fig. 6
From: Investigation of HCAR2 antagonists as a potential strategy to modulate bovine leukocytes
Log10-transformed cAMP concentrations of PMN cells. Forskolin (FSK; 0.1, 1, or 10 μmol/L) served as the positive control to increase cAMP. No FSK, NA-1, or NA-5 was the negative control (far left column). Treatments under the horizontal line were different from negative control (P ≤ 0.05). Asterisks within a column indicate effects of niacin or BHBA on cAMP (P ≤ 0.05). A BHB reduced cAMP when incubated with 10 or 100 μmol/L of NA-1. B Niacin increased cAMP but did not affect cAMP concentrations when incubated with NA-1 or NA-5