Effects of maternal methyl donor intake during pregnancy on ileum methylation and function in an intrauterine growth restriction pig model

Table 8 Effect of maternal MET supplementation on the DNA methylation level of ileum in newborn piglet

Item	Treatments				SEM	P-value
Item	CON_IUGR	CON_NBW	MET_IUGR	MET_NBW	SEM	BW	MET	BW × MET
5× Merged CG_MeanRate, %	65.00	64.47	65.32	65.23	0.94	0.62	0.39	0.73
5× CG_MeanRate, %	63.08^b	62.95^b	64.32^ab	65.87^a	1.11	0.03	0.43	0.36
Promoter, %	31.45	30.69	31.24	30.90	0.64	0.22	1.00	0.63

CON_IUGR CON group with IUGR piglets, CON_NBW CON group with NBW piglets, MET_IUGR MET group with IUGR piglets, MET_NBW MET group with NBW piglets
CG_MeanRate means the average methylation rate of CG type cytosine
^a,bP < 0.05 between different superscripts within the same line, n = 4 in each group

ISSN: 2049-1891