Table 1 Tissue-specific genes that overlapped with the genome-wide significant GPSM signals
From: Insights into the architecture of human-induced polygenic selection in Duroc pigs
Chra | Position | SNP | P-value | Geneb | Description | Tissuec | Type of orthologued |
|---|---|---|---|---|---|---|---|
1 | 68,477,634 | rs343429147 | 4.99 × 10−5 | GRIK2 | Glutamate ionotropic receptor kainate type subunit 2 | Cerebellum | 1-to-1* |
5 | 17,275,197 | rs325589813 | 2.22 × 10−5 | ACVRL1 | Activin A receptor like type 1 | Lung | 1-to-1* |
6 | 44,902,082 | rs333577047 | 9.06 × 10−6 | FFAR2 | Free fatty acid receptor 2 | Spleen | 1-to-1* |
6 | 45,249,022 | 6_45249022 | 1.34 × 10−5 | NPHS1 | NPHS1 adhesion molecule, nephrin | Kidney | 1-to-1* |
8 | 4,497,067 | rs325024132 | 2.96 × 10−6 | JAKMIP1 | Janus kinase and microtubule interacting protein 1 | Cerebrum | 1-to-1* |
8 | 126,046,420 | rs325782763 | 3.11 × 10−5 | GRID2 | Glutamate ionotropic receptor delta type subunit 2 | Cerebellum | 1-to-1* |
12 | 921,691 | rs321539153 | 5.40 × 10−5 | FASN | Fatty acid synthase | Fat | 1-to-1 |
12 | 1,136,822 | 12_1136822 | 5.40 × 10−5 | PPP1R27 | Protein phosphatase 1 regulatory subunit 27 | Muscle | 1-to-1* |
12 | 44,658,312 | rs694026589 | 5.71 × 10−5 | VTN | Vitronectin | Liver | 1-to-many* |
12 | 44,734,028 | rs328927732 | 1.99 × 10−5 | SLC13A2 | Solute carrier family 13 member 2 | Duodenum | 1-to-1* |
12 | 54,906,956 | rs329254243 | 2.18 × 10−5 | GAS7 | Growth arrest specific 7 | Cerebrum | 1-to-1* |
15 | 17,161,987 | rs322661315 | 6.29 × 10−5 | ACMSD | Aminocarboxymuconate semialdehyde decarboxylase | Kidney | 1-to-1* |
16 | 27,537,893 | rs335570719 | 6.74 × 10−6 | SELENOP | Selenoprotein P | Liver | 1-to-1* |
17 | 2,034,960 | 17_2034960 | 2.72 × 10−5 | SGCZ | Sarcoglycan zeta | Cerebrum | 1-to-1* |
17 | 9,824,048 | rs331351838 | 4.92 × 10−5 | ZMAT4 | Zinc finger matrin-type 4 | Cerebrum | 1-to-1* |