Fig. 9From: Differential transcriptional regulation of the NANOG gene in chicken primordial germ cells and embryonic stem cellsA model illustrating regulation of chicken NANOG (cNANOG) gene transcription in chicken primordial germ cells (PGCs) and embryonic stem cells (ESCs). cNANOG gene expression requires transcriptional trans-regulatory elements that are positively controlled by POU5F3 and SOX2 and negatively controlled by TP53 in PGCs. On the other hand, CCAAT/enhancer-binding protein (CEBP) positively regulates cNANOG gene expression in ESCsBack to article page